STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB78166.1Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (596 aa)    
Predicted Functional Partners:
SFB75056.1
PTS system, glucose-specific IIA component.
 0.990
SFB93603.1
Uncharacterized protein; PTS system D-fructose-specific IIA component (F1P-forming), Frc family (TC 4.A.2.1.4)/PTS system D-fructose-specific IIB component (F1P-forming), Frc family (TC 4.A.2.1.4)/PTS system D-fructose-specific IIC component (F1P-forming), Frc family (TC 4.A.2.1.4).
  
 
 0.979
SFB75007.1
Phosphocarrier protein.
  
 0.904
SFB79943.1
Phosphocarrier protein.
  
 0.904
SFB87596.1
PTS system, glucose-specific IIC component.
 
 
 0.889
SFB70525.1
PTS system, N-acetylglucosamine-specific IIC component.
 
 
 0.880
SFB74677.1
Phosphotransferase system IIB components.
  
 
 0.877
SFB81968.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.778
ruvA
Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.773
SFB78142.1
Protein of unknown function.
       0.752
Your Current Organism:
Brevinema andersonii
NCBI taxonomy Id: 34097
Other names: ATCC 43811, B. andersonii, strain CT11616
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.