STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmCtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (670 aa)    
Predicted Functional Partners:
SIR79247.1
Sarcosine oxidase subunit alpha.
  
 
 0.984
SIQ90168.1
Thiamine-phosphate diphosphorylase.
  
  
 0.589
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.574
SIR25495.1
Amino acid adenylation domain-containing protein.
  
  
 0.562
SIR68816.1
Cytochrome c556.
       0.550
SIQ46678.1
Ribosomal large subunit pseudouridine synthase A.
 
    0.544
SIR78950.1
tRNA 2-selenouridine synthase; Belongs to the SelU family.
  
   
 0.530
trmL
tRNA (cytidine/uridine-2'-O-)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
     
 0.520
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.515
SIR79228.1
Sarcosine oxidase subunit delta.
  
 
 0.497
Your Current Organism:
Sphaerotilus natans
NCBI taxonomy Id: 34103
Other names: ATCC 13338, Cladothrix dichotoma, DSM 6575, LMG 7172, LMG:7172, S. natans, Sphaerotilus dichotomus, Sphaerotilus fluitans, Streptothrix fluitans
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