STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIR79762.12-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)    
Predicted Functional Partners:
SIR79806.1
4-oxalocrotonate decarboxylase.
 
  
 0.809
SIR79783.1
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase.
 
  
 0.800
SIR79740.1
Catechol 2,3-dioxygenase.
 
  
 0.768
SIR79822.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
   
 0.719
SIR79842.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.698
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.680
SIR79857.1
Short-chain dehydrogenase.
  
   0.659
SIR25531.1
Acyl transferase domain-containing protein.
  
 
 0.607
SIR25495.1
Amino acid adenylation domain-containing protein.
  
 
 0.556
SIR79880.1
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family.
     
 0.553
Your Current Organism:
Sphaerotilus natans
NCBI taxonomy Id: 34103
Other names: ATCC 13338, Cladothrix dichotoma, DSM 6575, LMG 7172, LMG:7172, S. natans, Sphaerotilus dichotomus, Sphaerotilus fluitans, Streptothrix fluitans
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