STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (315 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.999
SFG01835.1
uroporphyrinogen-III synthase.
 0.999
SFG01872.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 0.999
SFG01784.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
 0.993
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
  
 0.983
SFG44523.1
Cobalt-precorrin 4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
   
 0.962
SFG71689.1
Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.951
SFG01763.1
Heptaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
  
 0.862
SFG01856.1
Putative heme d1 biosynthesis radical SAM protein NirJ1.
     
 0.823
SFG75550.1
Signal transduction histidine kinase.
  
 
 0.818
Your Current Organism:
Desulfallas arcticus
NCBI taxonomy Id: 341036
Other names: D. arcticus, DSM 17038, Desulfallas arcticus (Vandieken et al. 2006) Watanabe et al. 2018, Desulfotomaculum arcticum, Desulfotomaculum arcticum Vandieken et al. 2006, JCM 12923, low G+C Gram-positive bacterium 15, strain 15
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