STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4S2N3U83-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (370 aa)    
Predicted Functional Partners:
A0A4S2N2F9
Pantoate-beta-alanine ligase.
 
 0.998
A0A4S2MVN7
Dihydroxy-acid and 6-phosphogluconate dehydratase.
     
 0.905
A0A4S2N168
Dihydroxy-acid dehydratase.
     
 0.905
A0A4S2MJ37
Branched-chain amino acid aminotransferase II.
    
 0.881
A0A4S2MRJ7
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.881
A0A4V3SJH5
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.881
A0A4S2N6E0
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
     
 0.879
A0A4S2MN58
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
    
 0.790
A0A4S2N194
Rhodanese-like protein.
    
  0.763
A0A4S2MMY8
Glutathione degradosome.
     
 0.675
Your Current Organism:
Ascodesmis nigricans
NCBI taxonomy Id: 341454
Other names: A. nigricans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.