Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA01232.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.863
ORA00997.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.755
ORA00996.1
Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.731
OQZ94924.1
Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.652
ORA00892.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.624
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.620
OQZ94825.1
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.559
ORA01231.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.549
ORA00995.1
MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.536
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.528
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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