Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA01074.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.977
ORA00950.1
2,3-dihydroxybenzoate-AMP ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.975
ORA00825.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.967
ORA00604.1
Chorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.948
OQZ96138.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.942
ORA00948.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.926
OQZ94835.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.907
ORA00835.1
Salicylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.903
OQZ97138.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
  
 
 0.897
ORA00345.1
fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.894
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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