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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA00856.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 0.951
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.781
atpF
F0F1 ATP synthase subunit B/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family.
  
 
 0.748
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.726
ORA00055.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.705
ORA01245.1
Adenylyltransferase/sulfurtransferase MoeZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.672
OQZ96896.1
Cysteine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.632
OQZ96897.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.632
OQZ94141.1
Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.632
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.615
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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