Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA00933.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (309 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.917
ORA00934.1
Mandelate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
    0.916
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.901
OQZ94747.1
Alpha-ketoglutarate-dependent dioxygenase AlkB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.735
ORA00935.1
CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
       0.705
OQZ94669.1
Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
    
  0.596
ORA00932.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
ORA00939.1
methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.563
ORA00936.1
Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.558
ORA00938.1
acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.558
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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