Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA00442.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.926
ORA00444.1
8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.901
bioA
Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
     
 0.816
ORA00164.1
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
     
 0.699
OQZ98110.1
CPBP family intramembrane metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.554
ORA00446.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
gcvP
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.436
OQZ96380.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.421
OQZ95716.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.416
OQZ97105.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.410
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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