Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORA00131.1Zn-dependent protease with chaperone function; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)    
Predicted Functional Partners:
ORA00132.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.992
OQZ97768.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.910
OQZ90709.1
CopY family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.863
gndA
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.640
OQZ92268.1
Cell division protein FtsH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.
   
 0.584
ORA00133.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
ORA01242.1
Cytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.528
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.517
OQZ92562.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.478
OQZ95716.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.457
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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