Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORA00090.1DUF4126 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.628
hisE
phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.627
ORA00091.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.571
OQZ97845.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.560
OQZ96822.1
1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.550
OQZ98589.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.545
ORA00055.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.542
ORA01226.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.520
OQZ94687.1
Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.501
OQZ92033.1
Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.484
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.