Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
OQZ97421.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.718
OQZ98611.1
Peptigoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.677
OQZ96378.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
OQZ94381.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.636
OQZ90038.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.585
OQZ98148.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
ORA00389.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.577
OQZ94157.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
ORA00063.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
OQZ95678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.551
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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