Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OQZ96273.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)    
Predicted Functional Partners:
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
  
 
 
 0.982
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 
 
 0.949
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
   
 0.874
OQZ96272.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.874
OQZ96280.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.841
OQZ96270.1
Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.828
OQZ96271.1
Galactofuranosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.828
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
  
   
 0.773
ORA00047.1
Proteasome accessory factor PafA2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.690
OQZ96274.1
Cysteine desulfurase-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.624
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.