Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
OQZ96132.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.862
OQZ96870.1
Septation inhibitor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.753
OQZ96145.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.726
OQZ98621.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.710
ORA01258.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.705
OQZ96393.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.694
OQZ95571.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.682
OQZ97414.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.681
OQZ91807.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.660
OQZ99308.1
Resuscitation-promoting factor RpfA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.557
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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