Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
OQZ94624.13-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)    
Predicted Functional Partners:
OQZ94616.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.987
OQZ94599.1
Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.974
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.964
OQZ94667.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.962
ORA01191.1
Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.947
ORA01192.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.929
OQZ94601.1
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.928
ORA00187.1
23S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.898
ORA01170.1
FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.883
OQZ96818.1
2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.875
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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