STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OQZ92764.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)    
Predicted Functional Partners:
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.999
OQZ92769.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.958
OQZ92770.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.892
OQZ92765.1
Dynein regulation protein LC7; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.866
OQZ91843.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.609
pyk
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.518
OQZ98611.1
Peptigoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.507
OQZ92763.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.493
ORA00480.1
Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
  0.472
OQZ99983.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.457
Your Current Organism:
Mycolicibacter arupensis
NCBI taxonomy Id: 342002
Other names: DSM 44942, M. arupensis, Mycobacterium arupense, Mycobacterium arupense Cloud et al. 2006, Mycolicibacter arupensis (Cloud et al. 2006) Gupta et al. 2018, strain AR30097
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