| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amb0130 | amb0135 | amb0130 | amb0135 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 3-dehydroquinate synthetase. | 0.857 |
| amb0130 | amb0136 | amb0130 | amb0136 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.868 |
| amb0130 | aroA | amb0130 | amb4263 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.506 |
| amb0130 | aroB | amb0130 | amb3925 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.470 |
| amb0130 | aroC | amb0130 | amb1590 | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.674 |
| amb0135 | amb0130 | amb0135 | amb0130 | 3-dehydroquinate synthetase. | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.857 |
| amb0135 | amb0136 | amb0135 | amb0136 | 3-dehydroquinate synthetase. | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.817 |
| amb0135 | amb1219 | amb0135 | amb1219 | 3-dehydroquinate synthetase. | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. | 0.917 |
| amb0135 | aroA | amb0135 | amb4263 | 3-dehydroquinate synthetase. | 5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.986 |
| amb0135 | aroB | amb0135 | amb3925 | 3-dehydroquinate synthetase. | 3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.924 |
| amb0135 | aroC | amb0135 | amb1590 | 3-dehydroquinate synthetase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.962 |
| amb0135 | aroE | amb0135 | amb4547 | 3-dehydroquinate synthetase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.981 |
| amb0135 | aroK | amb0135 | amb0168 | 3-dehydroquinate synthetase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.841 |
| amb0135 | aroK-2 | amb0135 | amb3926 | 3-dehydroquinate synthetase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.994 |
| amb0135 | aroQ | amb0135 | amb2706 | 3-dehydroquinate synthetase. | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.950 |
| amb0136 | amb0130 | amb0136 | amb0130 | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.868 |
| amb0136 | amb0135 | amb0136 | amb0135 | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 3-dehydroquinate synthetase. | 0.817 |
| amb0136 | aroC | amb0136 | amb1590 | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.483 |
| amb1219 | amb0135 | amb1219 | amb0135 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. | 3-dehydroquinate synthetase. | 0.917 |
| amb1219 | aroB | amb1219 | amb3925 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. | 3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.929 |