node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amb0766 | amb0769 | amb0766 | amb0769 | Glycine cleavage system T protein. | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | 0.999 |
amb0766 | amb1683 | amb0766 | amb1683 | Glycine cleavage system T protein. | 7-keto-8-aminopelargonate synthetase and related enzyme. | 0.521 |
amb0766 | amb2321 | amb0766 | amb2321 | Glycine cleavage system T protein. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzyme. | 0.958 |
amb0766 | amb2464 | amb0766 | amb2464 | Glycine cleavage system T protein. | Serine-pyruvate aminotransferase. | 0.939 |
amb0766 | amb3963 | amb0766 | amb3963 | Glycine cleavage system T protein. | Pyruvate/2-oxoglutarate dehydrogenase complex; Dihydrolipoamide dehydrogenase (E3) component, and related enzyme. | 0.960 |
amb0766 | amb4448 | amb0766 | amb4448 | Glycine cleavage system T protein. | Putative aminotransferase MJ0959. | 0.939 |
amb0766 | gcvH | amb0766 | amb0767 | Glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
amb0766 | gcvPA | amb0766 | amb0768 | Glycine cleavage system T protein. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
amb0766 | glyA | amb0766 | amb2339 | Glycine cleavage system T protein. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
amb0766 | purQ | amb0766 | amb2114 | Glycine cleavage system T protein. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.828 |
amb0769 | amb0766 | amb0769 | amb0766 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Glycine cleavage system T protein. | 0.999 |
amb0769 | amb1683 | amb0769 | amb1683 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | 7-keto-8-aminopelargonate synthetase and related enzyme. | 0.929 |
amb0769 | amb2321 | amb0769 | amb2321 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzyme. | 0.939 |
amb0769 | amb2464 | amb0769 | amb2464 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Serine-pyruvate aminotransferase. | 0.915 |
amb0769 | amb3963 | amb0769 | amb3963 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Pyruvate/2-oxoglutarate dehydrogenase complex; Dihydrolipoamide dehydrogenase (E3) component, and related enzyme. | 0.940 |
amb0769 | amb4448 | amb0769 | amb4448 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Putative aminotransferase MJ0959. | 0.915 |
amb0769 | gcvH | amb0769 | amb0767 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
amb0769 | gcvPA | amb0769 | amb0768 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
amb0769 | glyA | amb0769 | amb2339 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.987 |
amb0769 | purQ | amb0769 | amb2114 | Glycine cleavage system protein P; (pyridoxal-binding), C-terminal domain. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.846 |