Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsZ | mamE | amb1015 | amb0963 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | 0.406 |
| ftsZ | mamK | amb1015 | amb0965 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Actin-like ATPase; Protein with ATPase activity which forms dynamic cytoplasmic filaments (probably with paralog MamK-like) that organize magnetosomes into long chains running parallel to the long axis of the cell (Probable). Turnover of MamK filaments is probably promoted by MamK-like, which provides a monomer pool. Forms twisted filaments in the presence of ATP or GTP. Serves to close gaps between magnetosomes in the chain. Interaction with MCP10 is involved in controlling the response to magnetic fields, possibly by controlling flagellar rotation. Expression in E.coli yields a filam [...] | 0.766 |
| ftsZ | mms13 | amb1015 | amb0951 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Tightly bound bacterial magnetic particle protein; Probably involved in magnetite crystal growth (Probable). The lumenal domain may bind the magnetite crystals, affecting crystal size and shape (Probable). | 0.616 |
| ftsZ | mms6 | amb1015 | amb0956 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Bacterial magnetic particle specific iron-binding protein; Promotes the formation of magnetite in Fe(2+)-rich conditions, when magnetite is not readily formed. Binds Fe(3+) and Fe(2+) (Probable). May play a role in nucleation of magnetite crystal formation (Probable). May help control production of crystals with a specific morphology (Probable). Greatly improves the formation of magnetosome-like magnetite crystals in vitro. Isolated short protein, probably residues 75-133, binds up to 18 Fe(3+) per monomer and self-assembles into micelles about 21-26 nm in diameter; the C-terminal 21 [...] | 0.616 |
| mamE | ftsZ | amb0963 | amb1015 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.406 |
| mamE | mamF | amb0963 | amb0953 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | 0.578 |
| mamE | mamI | amb0963 | amb0962 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Hypothetical protein; Essential for magnetosome formation. May bind magnetite (Probable). May be involved in an early stage of magnetosome nucleation (By similarity). | 0.905 |
| mamE | mamK | amb0963 | amb0965 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Actin-like ATPase; Protein with ATPase activity which forms dynamic cytoplasmic filaments (probably with paralog MamK-like) that organize magnetosomes into long chains running parallel to the long axis of the cell (Probable). Turnover of MamK filaments is probably promoted by MamK-like, which provides a monomer pool. Forms twisted filaments in the presence of ATP or GTP. Serves to close gaps between magnetosomes in the chain. Interaction with MCP10 is involved in controlling the response to magnetic fields, possibly by controlling flagellar rotation. Expression in E.coli yields a filam [...] | 0.897 |
| mamE | mamM | amb0963 | amb0967 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Predicted Co/Zn/Cd cation transporters; Probably plays a role in biomineralization (Probable). Required for stable accumulation of MamB (By similarity). Probably binds and transports iron. May nucleate iron crystal formation (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.806 |
| mamE | mamO | amb0963 | amb0969 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Trypsin-like serine protease; Plays 2 roles; promotes magnetite nucleation/formation and activates the MamE protease (Probable). Despite its near conservation of a protease-like sequence, this is probably not a protease (Probable). Required in conjunction with MamP for proteolysis of at least MamE, itself and MamP. May transport a solute that controls MamE's protease activity. May place individual iron atoms into the magnetite lattice (Probable). In the N-terminal section; belongs to the peptidase S1C family. | 0.638 |
| mamE | mms13 | amb0963 | amb0951 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Tightly bound bacterial magnetic particle protein; Probably involved in magnetite crystal growth (Probable). The lumenal domain may bind the magnetite crystals, affecting crystal size and shape (Probable). | 0.578 |
| mamE | mms6 | amb0963 | amb0956 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Bacterial magnetic particle specific iron-binding protein; Promotes the formation of magnetite in Fe(2+)-rich conditions, when magnetite is not readily formed. Binds Fe(3+) and Fe(2+) (Probable). May play a role in nucleation of magnetite crystal formation (Probable). May help control production of crystals with a specific morphology (Probable). Greatly improves the formation of magnetosome-like magnetite crystals in vitro. Isolated short protein, probably residues 75-133, binds up to 18 Fe(3+) per monomer and self-assembles into micelles about 21-26 nm in diameter; the C-terminal 21 [...] | 0.598 |
| mamE | mms7 | amb0963 | amb0952 | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | Tightly bound bacterial magnetic particle protein; Helps regulate magnetite crystal morphology, probably in a single growth axis. May help control oxido-reduction reactions surrounding the crystal lattice of the forming magnetite mineral (Probable). Probably binds Fe(2+), may play a role in nucleation of magnetite crystal formation (Probable). Expression in a deletion mutant restores growth of spherical (wild-type) magnetite crystals. Increased protein levels allow crystal growth in the minor axis but not increased numbers of crystals. | 0.578 |
| mamF | mamE | amb0953 | amb0963 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Trypsin-like serine protease, typically periplasmic; Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones. The 2 functions are separable by mutation. Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transport domain of MamO (Probable). Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome. | 0.578 |
| mamF | mamG | amb0953 | amb0954 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Bacterial magnetic particle specificiron-binding protein; Plays a role in regulating magnetite crystal size. Belongs to the magnetosome MamG (TC 9.B.95) protein family. | 0.832 |
| mamF | mamO | amb0953 | amb0969 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Trypsin-like serine protease; Plays 2 roles; promotes magnetite nucleation/formation and activates the MamE protease (Probable). Despite its near conservation of a protease-like sequence, this is probably not a protease (Probable). Required in conjunction with MamP for proteolysis of at least MamE, itself and MamP. May transport a solute that controls MamE's protease activity. May place individual iron atoms into the magnetite lattice (Probable). In the N-terminal section; belongs to the peptidase S1C family. | 0.404 |
| mamF | mms13 | amb0953 | amb0951 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Tightly bound bacterial magnetic particle protein; Probably involved in magnetite crystal growth (Probable). The lumenal domain may bind the magnetite crystals, affecting crystal size and shape (Probable). | 0.825 |
| mamF | mms6 | amb0953 | amb0956 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Bacterial magnetic particle specific iron-binding protein; Promotes the formation of magnetite in Fe(2+)-rich conditions, when magnetite is not readily formed. Binds Fe(3+) and Fe(2+) (Probable). May play a role in nucleation of magnetite crystal formation (Probable). May help control production of crystals with a specific morphology (Probable). Greatly improves the formation of magnetosome-like magnetite crystals in vitro. Isolated short protein, probably residues 75-133, binds up to 18 Fe(3+) per monomer and self-assembles into micelles about 21-26 nm in diameter; the C-terminal 21 [...] | 0.704 |
| mamF | mms7 | amb0953 | amb0952 | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | Tightly bound bacterial magnetic particle protein; Helps regulate magnetite crystal morphology, probably in a single growth axis. May help control oxido-reduction reactions surrounding the crystal lattice of the forming magnetite mineral (Probable). Probably binds Fe(2+), may play a role in nucleation of magnetite crystal formation (Probable). Expression in a deletion mutant restores growth of spherical (wild-type) magnetite crystals. Increased protein levels allow crystal growth in the minor axis but not increased numbers of crystals. | 0.821 |
| mamG | mamF | amb0954 | amb0953 | Bacterial magnetic particle specificiron-binding protein; Plays a role in regulating magnetite crystal size. Belongs to the magnetosome MamG (TC 9.B.95) protein family. | Hypothetical protein; Plays a role in regulating magnetite crystal size; partially redundant function with MmsF. | 0.832 |
page 1 of 4