| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amb0637 | amb2073 | amb0637 | amb2073 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | 0.546 |
| amb0637 | amb2569 | amb0637 | amb2569 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III, alpha subunit. | 0.857 |
| amb0637 | amb4290 | amb0637 | amb4290 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | ATPase involved in DNA replication. | 0.820 |
| amb0637 | dnaE2 | amb0637 | amb3000 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.813 |
| amb0637 | dnaX | amb0637 | amb4103 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III, gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.930 |
| amb0637 | polA | amb0637 | amb4211 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.983 |
| amb0637 | rplB | amb0637 | amb3127 | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.466 |
| amb1385 | amb2073 | amb1385 | amb2073 | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | 0.413 |
| amb1385 | rplB | amb1385 | amb3127 | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.731 |
| amb1428 | amb2073 | amb1428 | amb2073 | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | 0.413 |
| amb1428 | rplB | amb1428 | amb3127 | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.731 |
| amb2073 | amb0637 | amb2073 | amb0637 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.546 |
| amb2073 | amb1385 | amb2073 | amb1385 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | 0.413 |
| amb2073 | amb1428 | amb2073 | amb1428 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | 0.413 |
| amb2073 | amb2569 | amb2073 | amb2569 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | DNA polymerase III, alpha subunit. | 0.476 |
| amb2073 | amb4061 | amb2073 | amb4061 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | 0.413 |
| amb2073 | amb4290 | amb2073 | amb4290 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | ATPase involved in DNA replication. | 0.420 |
| amb2073 | dnaE2 | amb2073 | amb3000 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.476 |
| amb2073 | dnaX | amb2073 | amb4103 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | DNA polymerase III, gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.420 |
| amb2073 | polA | amb2073 | amb4211 | DNA polymerase III epsilon subunit and related 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.508 |