STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrCResponse regulator containing CheY-like receiver; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (487 aa)    
Predicted Functional Partners:
amb2366
Signal transduction histidine kinase; Nitrogen specific.
 0.998
amb2368
Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.889
amb2369
Response regulator containing CheY-like receiver; AAA-type ATPase, and DNA-binding domains.
 
    
0.858
amb2365
NifR3-like protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.839
amb2370
K+ transport systems, NAD-binding component.
      0.836
amb2371
Predicted phosphatase.
       0.826
amb3937
DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.802
hfq
Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 0.673
hflX
GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
  
 0.668
amb1872
PAS/PAC domain.
 
 
 0.644
Your Current Organism:
Magnetospirillum magneticum
NCBI taxonomy Id: 342108
Other names: M. magneticum AMB-1, Magnetospirillum magneticum AMB-1, Magnetospirillum magneticum str. AMB-1, Magnetospirillum magneticum strain AMB-1, Magnetospirillum sp. (strain AMB-1), Magnetospirillum sp. AMB-1
Server load: low (38%) [HD]