| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amb0429 | amb0521 | amb0429 | amb0521 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase [NADPH] large chain precursor. | 0.453 |
| amb0429 | amb1531 | amb0429 | amb1531 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. | 0.425 |
| amb0429 | amb1990 | amb0429 | amb1990 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-flavodoxin oxidoreductase. | 0.548 |
| amb0429 | amb3193 | amb0429 | amb3193 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.642 |
| amb0429 | amb3194 | amb0429 | amb3194 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine aminotransferase. | 0.419 |
| amb0429 | amb3728 | amb0429 | amb3728 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase. | 0.949 |
| amb0429 | cysC | amb0429 | amb2212 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NodQ bifunctional enzyme; Catalyzes the synthesis of activated sulfate. | 0.601 |
| amb0521 | amb0429 | amb0521 | amb0429 | Glutamate synthase [NADPH] large chain precursor. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.453 |
| amb0521 | amb1531 | amb0521 | amb1531 | Glutamate synthase [NADPH] large chain precursor. | Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. | 0.517 |
| amb0521 | amb1990 | amb0521 | amb1990 | Glutamate synthase [NADPH] large chain precursor. | Pyruvate-flavodoxin oxidoreductase. | 0.614 |
| amb0521 | amb3193 | amb0521 | amb3193 | Glutamate synthase [NADPH] large chain precursor. | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.531 |
| amb0521 | amb3194 | amb0521 | amb3194 | Glutamate synthase [NADPH] large chain precursor. | Phosphoserine aminotransferase. | 0.517 |
| amb0521 | amb3728 | amb0521 | amb3728 | Glutamate synthase [NADPH] large chain precursor. | Homoserine dehydrogenase. | 0.620 |
| amb0521 | cysC | amb0521 | amb2212 | Glutamate synthase [NADPH] large chain precursor. | NodQ bifunctional enzyme; Catalyzes the synthesis of activated sulfate. | 0.542 |
| amb0521 | gpmI | amb0521 | amb0305 | Glutamate synthase [NADPH] large chain precursor. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.561 |
| amb0521 | nadE | amb0521 | amb1233 | Glutamate synthase [NADPH] large chain precursor. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.572 |
| amb0521 | purA | amb0521 | amb3190 | Glutamate synthase [NADPH] large chain precursor. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.402 |
| amb1531 | amb0429 | amb1531 | amb0429 | Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.425 |
| amb1531 | amb0521 | amb1531 | amb0521 | Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. | Glutamate synthase [NADPH] large chain precursor. | 0.517 |
| amb1531 | amb3193 | amb1531 | amb3193 | Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family. | Phosphoglycerate dehydrogenase and related dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.908 |