| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | acsA | amb2554 | amb4177 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.929 |
| ackA | amb1383 | amb2554 | amb1383 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acetyl-CoA hydrolase. | 0.922 |
| ackA | amb1422 | amb2554 | amb1422 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. | 0.929 |
| ackA | amb2507 | amb2554 | amb2507 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Delta 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.433 |
| ackA | amb2593 | amb2554 | amb2593 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.928 |
| ackA | amb3595 | amb2554 | amb3595 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.928 |
| ackA | amb3815 | amb2554 | amb3815 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. | 0.925 |
| acsA | ackA | amb4177 | amb2554 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.929 |
| acsA | amb1383 | amb4177 | amb1383 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-CoA hydrolase. | 0.934 |
| acsA | amb1422 | amb4177 | amb1422 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. | 0.916 |
| acsA | amb2507 | amb4177 | amb2507 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Delta 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.487 |
| acsA | amb2593 | amb4177 | amb2593 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.940 |
| acsA | amb3584 | amb4177 | amb3584 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. | 0.523 |
| acsA | amb3587 | amb4177 | amb3587 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase. | 0.821 |
| acsA | amb3595 | amb4177 | amb3595 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.940 |
| acsA | amb3815 | amb4177 | amb3815 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. | 0.927 |
| amb1383 | ackA | amb1383 | amb2554 | Acetyl-CoA hydrolase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.922 |
| amb1383 | acsA | amb1383 | amb4177 | Acetyl-CoA hydrolase. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.934 |
| amb1383 | amb1422 | amb1383 | amb1422 | Acetyl-CoA hydrolase. | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. | 0.934 |
| amb1383 | amb2593 | amb1383 | amb2593 | Acetyl-CoA hydrolase. | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.912 |