| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amb0906 | amb1417 | amb0906 | amb1417 | Superfamily II DNA/RNA helicase. | Superfamily I DNA and RNA helicase. | 0.451 |
| amb0906 | amb4061 | amb0906 | amb4061 | Superfamily II DNA/RNA helicase. | Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. | 0.707 |
| amb0906 | amb4254 | amb0906 | amb4254 | Superfamily II DNA/RNA helicase. | Superfamily II DNA helicase. | 0.845 |
| amb0906 | gmk | amb0906 | amb0748 | Superfamily II DNA/RNA helicase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.680 |
| amb0906 | polA | amb0906 | amb4211 | Superfamily II DNA/RNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.939 |
| amb0906 | recA | amb0906 | amb0622 | Superfamily II DNA/RNA helicase. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.838 |
| amb0906 | topA | amb0906 | amb0682 | Superfamily II DNA/RNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.774 |
| amb1417 | amb0906 | amb1417 | amb0906 | Superfamily I DNA and RNA helicase. | Superfamily II DNA/RNA helicase. | 0.451 |
| amb1417 | amb4254 | amb1417 | amb4254 | Superfamily I DNA and RNA helicase. | Superfamily II DNA helicase. | 0.813 |
| amb1417 | mutL | amb1417 | amb4416 | Superfamily I DNA and RNA helicase. | DNA mismatch repair enzyme; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.717 |
| amb1417 | polA | amb1417 | amb4211 | Superfamily I DNA and RNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.658 |
| amb1417 | recA | amb1417 | amb0622 | Superfamily I DNA and RNA helicase. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.818 |
| amb1417 | topA | amb1417 | amb0682 | Superfamily I DNA and RNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.671 |
| amb2449 | amb4254 | amb2449 | amb4254 | ATPase involved in DNA replication. | Superfamily II DNA helicase. | 0.787 |
| amb2449 | mutL | amb2449 | amb4416 | ATPase involved in DNA replication. | DNA mismatch repair enzyme; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.475 |
| amb2449 | polA | amb2449 | amb4211 | ATPase involved in DNA replication. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.896 |
| amb2449 | recA | amb2449 | amb0622 | ATPase involved in DNA replication. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.692 |
| amb2449 | topA | amb2449 | amb0682 | ATPase involved in DNA replication. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.724 |
| amb3730 | amb4254 | amb3730 | amb4254 | Single-stranded DNA-specific exonuclease. | Superfamily II DNA helicase. | 0.921 |
| amb3730 | mutL | amb3730 | amb4416 | Single-stranded DNA-specific exonuclease. | DNA mismatch repair enzyme; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.608 |