Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amb4400Aconitase B; Belongs to the aconitase/IPM isomerase family. (886 aa)    
Predicted Functional Partners:
amb0608
Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.986
amb2804
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.972
amb0607
Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.946
amb3651
Aconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.939
mdh
Malate/lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.917
amb3961
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzyme.
   
  
 0.893
sucC
Succinyl-CoA synthetase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.886
amb1331
Fumarate hydratase class I aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.825
amb3950
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
  
 0.647
amb1990
Pyruvate-flavodoxin oxidoreductase.
   
  
 0.603
Your Current Organism:
Magnetospirillum magneticum
NCBI taxonomy Id: 342108
Other names: M. magneticum AMB-1, Magnetospirillum magneticum AMB-1, Magnetospirillum magneticum str. AMB-1, Magnetospirillum magneticum strain AMB-1, Magnetospirillum sp. (strain AMB-1), Magnetospirillum sp. AMB-1
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