| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amb0085 | amb4549 | amb0085 | amb4549 | Nucleoside-diphosphate-sugar pyrophosphorylase; eIF-2Bgamma/eIF-2Bepsilon; involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits. | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.491 |
| amb0572 | amb4549 | amb0572 | amb4549 | CBS domain. | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.491 |
| amb1214 | amb4549 | amb1214 | amb4549 | Predicted signal transduction protein; EAL and a GGDEF domain; containing a membrane domain. | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.565 |
| amb2649 | amb4549 | amb2649 | amb4549 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.833 |
| amb2649 | glyS | amb2649 | amb2650 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. | Glycyl-tRNA synthetase; Beta subunit. | 0.677 |
| amb4548 | amb4549 | amb4548 | amb4549 | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | 0.837 |
| amb4548 | aroE | amb4548 | amb4547 | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.950 |
| amb4548 | coaE | amb4548 | amb4546 | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.902 |
| amb4548 | dnaQ | amb4548 | amb4545 | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | DNA polymerase III, epsilon subunit and related 3'-5' exonuclease; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.865 |
| amb4548 | hemE | amb4548 | amb4550 | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.596 |
| amb4549 | amb0085 | amb4549 | amb0085 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Nucleoside-diphosphate-sugar pyrophosphorylase; eIF-2Bgamma/eIF-2Bepsilon; involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits. | 0.491 |
| amb4549 | amb0572 | amb4549 | amb0572 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | CBS domain. | 0.491 |
| amb4549 | amb1214 | amb4549 | amb1214 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Predicted signal transduction protein; EAL and a GGDEF domain; containing a membrane domain. | 0.565 |
| amb4549 | amb2649 | amb4549 | amb2649 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. | 0.833 |
| amb4549 | amb4548 | amb4549 | amb4548 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.837 |
| amb4549 | aroE | amb4549 | amb4547 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.837 |
| amb4549 | coaE | amb4549 | amb4546 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.837 |
| amb4549 | dnaQ | amb4549 | amb4545 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | DNA polymerase III, epsilon subunit and related 3'-5' exonuclease; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.837 |
| amb4549 | glyS | amb4549 | amb2650 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Glycyl-tRNA synthetase; Beta subunit. | 0.537 |
| amb4549 | hemE | amb4549 | amb4550 | Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.600 |