| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | icd | DM82_1903 | DM82_286 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | 0.425 |
| aceF | lpdA | DM82_1903 | DM82_1037 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.993 |
| aceF | lpdA-2 | DM82_1903 | DM82_1902 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.989 |
| aceF | lpdA-3 | DM82_1903 | DM82_4061 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.995 |
| aceF | sucA | DM82_1903 | DM82_1035 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component. | 0.983 |
| aceF | sucB | DM82_1903 | DM82_1036 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.452 |
| aceF | sucC | DM82_1903 | DM82_172 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.960 |
| aceF | sucD | DM82_1903 | DM82_173 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.934 |
| bkdB | icd | DM82_4060 | DM82_286 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | 0.425 |
| bkdB | lpdA | DM82_4060 | DM82_1037 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.991 |
| bkdB | lpdA-2 | DM82_4060 | DM82_1902 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.990 |
| bkdB | lpdA-3 | DM82_4060 | DM82_4061 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.999 |
| bkdB | pdhC | DM82_4060 | DM82_3775 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | E3 binding domain protein. | 0.923 |
| bkdB | sucA | DM82_4060 | DM82_1035 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component. | 0.965 |
| bkdB | sucC | DM82_4060 | DM82_172 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.810 |
| bkdB | sucD | DM82_4060 | DM82_173 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.683 |
| icd | aceF | DM82_286 | DM82_1903 | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.425 |
| icd | bkdB | DM82_286 | DM82_4060 | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.425 |
| icd | lpdA | DM82_286 | DM82_1037 | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.437 |
| icd | lpdA-2 | DM82_286 | DM82_1902 | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | lipoamide_DH: dihydrolipoyl dehydrogenase. | 0.738 |