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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (330 aa)    
Predicted Functional Partners:
pyrK
Oxidoreductase FAD-binding domain protein.
  
 0.996
pyrC
Dihydroorotase; Multifunctional complex type domain protein; pyrC_multi: dihydroorotase, multifunctional complex type domain protein.
  
 0.989
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.989
pyrC-2
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.988
ascD
2Fe-2S iron-sulfur cluster binding domain protein.
  
 
 0.961
carB
CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 
 0.939
carA
CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 
  
 0.937
pyrF
pyrF_sub2: orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.914
pyrDB
Dihydroorotate dehydrogenase family domain protein; Catalyzes the conversion of dihydroorotate to orotate.
     
 
0.900
pheT
pheT_bact: phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.893
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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