Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
cobIPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (244 aa)    
Predicted Functional Partners:
cobJ
cobJ_cbiH: precorrin-3B C17-methyltransferase.
 
 0.999
cobH
precorrin-8X methylmutase family protein.
  
 0.997
cobG
cobG: precorrin-3B synthase.
 
 
 0.994
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit.
 
  
 0.984
cobK
Precorrin-6x reductase CbiJ/CobK family protein.
 
  
 0.983
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.958
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.951
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.951
cobA-2
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase.
 
 
 0.950
cobM
cobM_cbiF: precorrin-4 C11-methyltransferase.
 
  
0.946
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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