Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mvaAHydroxymethylglutaryl-coenzyme A reductase family protein. (408 aa)    
Predicted Functional Partners:
accA1_1
D-ala D-ala ligase family protein.
       0.779
accD5
propionyl-CoA carboxylase, beta subunit.
       0.753
cfiA
Biotin-requiring enzyme family protein.
       0.620
hflB-2
ftsH_fam: ATP-dependent metallopeptidase HflB family protein; Belongs to the AAA ATPase family.
  
 
 
 0.562
DM82_1345
Hypothetical protein.
       0.496
DM82_6355
AMP-binding enzyme family protein.
 
 
 0.459
DM82_1351
mmgE/PrpD family protein.
       0.447
DM82_1596
Isochorismatase family protein.
 
      0.439
ispB
Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.435
ispA_1
Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.433
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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