| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM82_1437 | acs | DM82_1437 | DM82_4474 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
| DM82_1437 | bclA_1 | DM82_1437 | DM82_820 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | AMP-binding enzyme family protein. | 0.927 |
| DM82_1437 | bclA_2 | DM82_1437 | DM82_4713 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | AMP-binding enzyme family protein. | 0.927 |
| DM82_1437 | fadJ_1 | DM82_1437 | DM82_3222 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | enoyl-CoA hydratase/isomerase family protein. | 0.914 |
| DM82_1437 | flhA_2 | DM82_1437 | DM82_212 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.915 |
| DM82_1437 | gabD_1 | DM82_1437 | DM82_5641 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase family protein. | 0.919 |
| DM82_1437 | gabT-2 | DM82_1437 | DM82_4283 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | GABAtrnsam: 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.920 |
| DM82_1437 | mmsA | DM82_1437 | DM82_3145 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.917 |
| DM82_1437 | mmsA-2 | DM82_1437 | DM82_4714 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.918 |
| DM82_1437 | mmsA-3 | DM82_1437 | DM82_4845 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.917 |
| acs | DM82_1437 | DM82_4474 | DM82_1437 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.927 |
| acs | bclA_1 | DM82_4474 | DM82_820 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-binding enzyme family protein. | 0.914 |
| acs | bclA_2 | DM82_4474 | DM82_4713 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-binding enzyme family protein. | 0.921 |
| acs | fadJ_1 | DM82_4474 | DM82_3222 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | enoyl-CoA hydratase/isomerase family protein. | 0.929 |
| acs | gabD_1 | DM82_4474 | DM82_5641 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein. | 0.927 |
| acs | mmsA | DM82_4474 | DM82_3145 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.927 |
| acs | mmsA-2 | DM82_4474 | DM82_4714 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.927 |
| acs | mmsA-3 | DM82_4474 | DM82_4845 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.927 |
| bclA_1 | DM82_1437 | DM82_820 | DM82_1437 | AMP-binding enzyme family protein. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.927 |
| bclA_1 | acs | DM82_820 | DM82_4474 | AMP-binding enzyme family protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.914 |