| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaA | guaB | DM82_1711 | DM82_1713 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | hpt | DM82_1711 | DM82_2662 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosyl transferase domain protein. | 0.947 |
| guaA | purA | DM82_1711 | DM82_1481 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.929 |
| guaA | purB | DM82_1711 | DM82_2590 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | purB: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.831 |
| guaA | purH | DM82_1711 | DM82_2566 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.931 |
| guaA | purL | DM82_1711 | DM82_1604 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.974 |
| guaA | pyrB | DM82_1711 | DM82_2352 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.638 |
| guaA | pyrB-2 | DM82_1711 | DM82_5340 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.674 |
| guaA | surE | DM82_1711 | DM82_1503 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.945 |
| guaB | guaA | DM82_1713 | DM82_1711 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | hpt | DM82_1713 | DM82_2662 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosyl transferase domain protein. | 0.945 |
| guaB | purA | DM82_1713 | DM82_1481 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.994 |
| guaB | purB | DM82_1713 | DM82_2590 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | purB: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.878 |
| guaB | purH | DM82_1713 | DM82_2566 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.976 |
| guaB | purL | DM82_1713 | DM82_1604 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.804 |
| guaB | pyrB | DM82_1713 | DM82_2352 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.566 |
| guaB | pyrB-2 | DM82_1713 | DM82_5340 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.530 |
| guaB | surE | DM82_1713 | DM82_1503 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.940 |
| hpt | guaA | DM82_2662 | DM82_1711 | Phosphoribosyl transferase domain protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.947 |
| hpt | guaB | DM82_2662 | DM82_1713 | Phosphoribosyl transferase domain protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.945 |
STRING v12.5 is now available!
