Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ispZIntracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (176 aa)    
Predicted Functional Partners:
bolA
bolA-like family protein; Belongs to the BolA/IbaG family.
 
    0.903
cbf2
PPIC-type PPIASE domain protein.
       0.828
msrB
Peptide methionine sulfoxide reductase MsrB.
  
    0.794
selO
Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.
       0.637
DM82_66
Tim44-like domain protein.
  
     0.478
thrB
thrB_alt: homoserine kinase; Belongs to the pseudomonas-type ThrB family.
  
   
 0.474
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component.
      
 0.424
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
       0.414
secB
Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.402
gltK
HEQRo_perm_3TM: amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein.
      
 0.401
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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