| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | scpC_1 | DM82_1903 | DM82_4616 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | ygfH_subfam: succinate CoA transferase family protein. | 0.912 |
| aceF | sdhA | DM82_1903 | DM82_5965 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | sdhA_forward: succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.603 |
| aceF | sdhB | DM82_1903 | DM82_5964 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.661 |
| aceF | sdhC | DM82_1903 | DM82_5967 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit. | 0.487 |
| aceF | sdhD | DM82_1903 | DM82_5966 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein. | 0.472 |
| aceF | sucA | DM82_1903 | DM82_1035 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component. | 0.983 |
| aceF | sucB | DM82_1903 | DM82_1036 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.452 |
| aceF | sucC | DM82_1903 | DM82_172 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.960 |
| aceF | sucD | DM82_1903 | DM82_173 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.934 |
| scpC_1 | aceF | DM82_4616 | DM82_1903 | ygfH_subfam: succinate CoA transferase family protein. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.912 |
| scpC_1 | sdhA | DM82_4616 | DM82_5965 | ygfH_subfam: succinate CoA transferase family protein. | sdhA_forward: succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.914 |
| scpC_1 | sdhB | DM82_4616 | DM82_5964 | ygfH_subfam: succinate CoA transferase family protein. | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.921 |
| scpC_1 | sdhC | DM82_4616 | DM82_5967 | ygfH_subfam: succinate CoA transferase family protein. | succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit. | 0.906 |
| scpC_1 | sdhD | DM82_4616 | DM82_5966 | ygfH_subfam: succinate CoA transferase family protein. | Succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein. | 0.900 |
| scpC_1 | sucB | DM82_4616 | DM82_1036 | ygfH_subfam: succinate CoA transferase family protein. | Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.912 |
| scpC_1 | sucC | DM82_4616 | DM82_172 | ygfH_subfam: succinate CoA transferase family protein. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.941 |
| scpC_1 | sucD | DM82_4616 | DM82_173 | ygfH_subfam: succinate CoA transferase family protein. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.955 |
| scpC_2 | sucC | DM82_5765 | DM82_172 | Hypothetical protein; acetyl-CoA hydrolase/transferase N-terminal domain protein. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.941 |
| scpC_2 | sucD | DM82_5765 | DM82_173 | Hypothetical protein; acetyl-CoA hydrolase/transferase N-terminal domain protein. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.955 |
| sdhA | aceF | DM82_5965 | DM82_1903 | sdhA_forward: succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.603 |
