| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aaeB_2 | yoaE_1 | DM82_4868 | DM82_174 | Fusaric acid resistance family protein. | R_switched_YjbE: integral membrane, YjbE family protein. | 0.401 |
| fimA_4 | sucD | DM82_175 | DM82_173 | Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.426 |
| fimA_4 | yoaE_1 | DM82_175 | DM82_174 | Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein. | R_switched_YjbE: integral membrane, YjbE family protein. | 0.571 |
| nnr | yoaE_1 | DM82_1606 | DM82_174 | Hydroxyethylthiazole kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow [...] | R_switched_YjbE: integral membrane, YjbE family protein. | 0.414 |
| sucC | sucD | DM82_172 | DM82_173 | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.999 |
| sucC | yoaE_1 | DM82_172 | DM82_174 | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | R_switched_YjbE: integral membrane, YjbE family protein. | 0.612 |
| sucD | fimA_4 | DM82_173 | DM82_175 | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein. | 0.426 |
| sucD | sucC | DM82_173 | DM82_172 | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |
| sucD | yoaE_1 | DM82_173 | DM82_174 | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | R_switched_YjbE: integral membrane, YjbE family protein. | 0.708 |
| yoaE_1 | aaeB_2 | DM82_174 | DM82_4868 | R_switched_YjbE: integral membrane, YjbE family protein. | Fusaric acid resistance family protein. | 0.401 |
| yoaE_1 | fimA_4 | DM82_174 | DM82_175 | R_switched_YjbE: integral membrane, YjbE family protein. | Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein. | 0.571 |
| yoaE_1 | nnr | DM82_174 | DM82_1606 | R_switched_YjbE: integral membrane, YjbE family protein. | Hydroxyethylthiazole kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow [...] | 0.414 |
| yoaE_1 | sucC | DM82_174 | DM82_172 | R_switched_YjbE: integral membrane, YjbE family protein. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.612 |
| yoaE_1 | sucD | DM82_174 | DM82_173 | R_switched_YjbE: integral membrane, YjbE family protein. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.708 |
