Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mucD_2degP_htrA_DO: peptidase Do family protein; Belongs to the peptidase S1C family. (502 aa)    
Predicted Functional Partners:
DM82_2055
Hypothetical protein; Anti sigma-E RseA, N-terminal domain protein.
  
 
 0.956
mucD_1
PDZ domain protein.
  
  
 
0.915
mucD_3
degP_htrA_DO: peptidase Do family protein; Belongs to the peptidase S1C family.
  
  
 
0.906
DM82_2052
Hypothetical protein.
  
   0.875
rseB
mucB/RseB family protein.
  
  
 0.820
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.713
lepB
sigpep_I_bact: signal peptidase I; Belongs to the peptidase S26 family.
 
   
 0.670
rpoE
rpoE_Sigma70: RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.590
rplY
Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
 
   0.584
ppsE_2
AMP-binding enzyme family protein.
  
 0.584
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.