Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mexAMultidrug resistance protein mexA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (423 aa)    
Predicted Functional Partners:
acrB_2
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein.
 0.997
acrB_1
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein.
 0.970
oprM
Outer membrane protein oprM.
 
 
 0.964
mdtE_1
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.951
mdtC_1
MMPL family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.947
oprM_3
Outer membrane efflux family protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 0.944
tolC
Outer membrane efflux family protein.
  
 0.937
czcA_2
acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.932
macB_1
ABC transporter family protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.927
acrB_3
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein.
 
 0.910
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.