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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ghrB_2D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. (329 aa)    
Predicted Functional Partners:
glxK_1
Glycerate kinase family protein; Belongs to the glycerate kinase type-1 family.
 
  
 0.920
garK
Glycerate kinase 2; Belongs to the glycerate kinase type-1 family.
 
  
 0.920
ghrA_2
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
 
  
 
0.920
ghrA_1
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
 
  
 
0.918
gph-2
Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
  0.915
aceB
malate_syn_A: malate synthase A; Belongs to the malate synthase family.
  
 
 0.912
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.912
aceA
Isocit_lyase: isocitrate lyase.
     
 0.909
gnl_2
Strictosidine synthase family protein.
  
 
 0.909
ghrB
Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.908
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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