Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
hemLhemL: glutamate-1-semialdehyde-2,1-aminomutase. (427 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family.
 
 
 0.990
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.988
hemL1
Aminotransferase class-III family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.919
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.913
ribE
ribE: riboflavin synthase, alpha subunit.
     
 0.801
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.782
dhbF_2
AA-adenyl-dom: amino acid adenylation domain protein; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.749
cobA-2
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase.
 
   
 0.695
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.691
lgrD_1
NRPS-para261: non-ribosomal peptide synthase TIGR01720 domain protein.
  
  
 0.689
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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