close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhAD-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. (334 aa)    
Predicted Functional Partners:
maeB_1
Malic enzyme, NAD binding domain protein.
   
 0.935
maeB
NADP-dependent malic enzyme; Belongs to the malic enzymes family.
   
 0.935
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.924
pyk-2
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.924
pyk-3
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.924
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
 0.919
lldD
Hypothetical protein; Conserved region in glutamate synthase family protein.
  
 
 0.916
mdlB_3
FMN-dependent dehydrogenase family protein.
  
 
 0.916
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.914
pflB
Pyr_form_ly_1: formate acetyltransferase.
     
 0.912
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.