Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ldhAD-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. (334 aa)    
Predicted Functional Partners:
maeB_1
Malic enzyme, NAD binding domain protein.
   
 0.932
maeB
NADP-dependent malic enzyme; Belongs to the malic enzymes family.
   
 0.932
mdlB_3
FMN-dependent dehydrogenase family protein.
  
 
 0.927
lldD
Hypothetical protein; Conserved region in glutamate synthase family protein.
  
 
 0.924
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.923
pyk-2
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.923
pyk-3
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.923
DM82_2514
FAD binding domain protein.
   
 0.921
DM82_5501
FAD binding domain protein.
   
 0.921
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.917
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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