| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM82_2507 | glnE | DM82_2507 | DM82_2506 | Hypothetical protein. | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | 0.655 |
| DM82_2507 | ramA | DM82_2507 | DM82_2508 | Hypothetical protein. | Carbon-nitrogen hydrolase family protein. | 0.746 |
| DM82_2507 | tldD_1 | DM82_2507 | DM82_2509 | Hypothetical protein. | Modulator of DNA gyrase family protein. | 0.611 |
| glnE | DM82_2507 | DM82_2506 | DM82_2507 | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | Hypothetical protein. | 0.655 |
| glnE | ramA | DM82_2506 | DM82_2508 | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | Carbon-nitrogen hydrolase family protein. | 0.591 |
| glnE | tldD_1 | DM82_2506 | DM82_2509 | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | Modulator of DNA gyrase family protein. | 0.451 |
| pmbA | tldD_1 | DM82_2104 | DM82_2509 | Modulator of DNA gyrase family protein. | Modulator of DNA gyrase family protein. | 0.877 |
| pmbA | zapD | DM82_2104 | DM82_2678 | Modulator of DNA gyrase family protein. | Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.565 |
| ramA | DM82_2507 | DM82_2508 | DM82_2507 | Carbon-nitrogen hydrolase family protein. | Hypothetical protein. | 0.746 |
| ramA | glnE | DM82_2508 | DM82_2506 | Carbon-nitrogen hydrolase family protein. | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | 0.591 |
| ramA | tldD_1 | DM82_2508 | DM82_2509 | Carbon-nitrogen hydrolase family protein. | Modulator of DNA gyrase family protein. | 0.646 |
| tldD_1 | DM82_2507 | DM82_2509 | DM82_2507 | Modulator of DNA gyrase family protein. | Hypothetical protein. | 0.611 |
| tldD_1 | glnE | DM82_2509 | DM82_2506 | Modulator of DNA gyrase family protein. | Glutamate-ammonia ligase adenylyltransferase family protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds th [...] | 0.451 |
| tldD_1 | pmbA | DM82_2509 | DM82_2104 | Modulator of DNA gyrase family protein. | Modulator of DNA gyrase family protein. | 0.877 |
| tldD_1 | ramA | DM82_2509 | DM82_2508 | Modulator of DNA gyrase family protein. | Carbon-nitrogen hydrolase family protein. | 0.646 |
| tldD_1 | zapD | DM82_2509 | DM82_2678 | Modulator of DNA gyrase family protein. | Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.404 |
| zapD | pmbA | DM82_2678 | DM82_2104 | Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | Modulator of DNA gyrase family protein. | 0.565 |
| zapD | tldD_1 | DM82_2678 | DM82_2509 | Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | Modulator of DNA gyrase family protein. | 0.404 |
STRING v12.5 is now available!
