Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
epsE_1Type II/IV secretion system family protein. (425 aa)    
Predicted Functional Partners:
gspF-2
Type II secretion system (T2SS), F family protein.
 
 
 0.994
outO
Type IV leader peptidase family protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.968
gspF
gspF: type II secretion system protein F.
 
 
 0.965
epsF_2
Type II secretion system (T2SS), F family protein.
 
 
 0.944
gspG
typeII_sec_gspG: type II secretion system protein G.
 
 
 0.904
pilQ
IV_pilus_PilQ: type IV pilus secretin PilQ family protein.
 
 
 
 0.850
gspL
typeII_sec_gspL: type II secretion system protein L.
  
 
 0.838
DM82_1878
comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.734
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
     
 0.714
xpsD_1
Bacterial type II and III secretion system family protein; Belongs to the bacterial secretin family.
 
  
 0.710
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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