Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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acoDAcetaldehyde dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.922
bclA_2
AMP-binding enzyme family protein.
  
 0.919
scpC_1
ygfH_subfam: succinate CoA transferase family protein.
 
 
 0.916
poxB
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family.
 
 0.916
flhA_2
adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.914
DM82_1437
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.913
puuC_1
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.912
yahK
Zinc-binding dehydrogenase family protein.
  
 0.911
DM82_6209
Adh_fam_2: zinc-binding alcohol dehydrogenase family protein.
  
 0.911
DM82_6236
Zinc-binding dehydrogenase family protein.
  
 0.911
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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