Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pcbd1Pterin-4-alpha-carbinolamine dehydratase. (101 aa)    
Predicted Functional Partners:
phhA
Phe4hydrox_mono: phenylalanine-4-hydroxylase.
 
 0.997
hppD
4HPPD: 4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.874
fahA
Fum_ac_acetase: fumarylacetoacetase.
 
  
 0.773
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.757
hpd_2
Xylose isomerase-like TIM barrel family protein.
  
  
 0.617
maiA
maiA: maleylacetoacetate isomerase.
 
  
 0.570
tyrB_3
Aminotransferase class I and II family protein.
  
  
 0.539
tyrB
Aromatic-amino-acid aminotransferase.
  
  
 0.534
tyrB_1
Aminotransferase class I and II family protein.
  
  
 0.534
DM82_5558
Dihydroneopterin aldolase family protein.
     
 0.475
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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