Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
czcC_1Outer membrane efflux family protein. (432 aa)    
Predicted Functional Partners:
cusB
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.984
cusA
2A0601: heavy metal efflux pump, CzcA family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.972
DM82_3527
Copper binding periplasmic CusF family protein.
 
 
 0.918
DM82_4554
Copper resistance D family protein.
 
     0.676
macB_1
ABC transporter family protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.661
czcA
Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.615
DM82_3523
Hypothetical protein.
       0.601
DM82_6126
tonB dependent receptor family protein.
  
   
 0.550
acsC
Cellulose synthase operon C family protein.
  
     0.544
DM82_5046
Gram-negative porin family protein.
  
     0.533
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.