Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
csgAShort chain dehydrogenase family protein. (225 aa)    
Predicted Functional Partners:
ychJ
Putative protein YchJ.
 
     0.845
can_1
Carbonic anhydrase family protein.
       0.799
lgrD_1
NRPS-para261: non-ribosomal peptide synthase TIGR01720 domain protein.
  
 
 0.737
tycC_2
AA-adenyl-dom: amino acid adenylation domain protein.
  
 
 0.737
thlA_2
acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family.
       0.696
aceK
Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.609
DM82_3583
phospholipase/Carboxylesterase family protein.
       0.511
DM82_6361
AMP-binding enzyme family protein.
  
 
 0.474
dltA-2
D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1.
  
 
 0.463
ppsE_2
AMP-binding enzyme family protein.
  
 
 0.416
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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