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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
can_1Carbonic anhydrase family protein. (256 aa)    
Predicted Functional Partners:
cynS
Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
  
 
 0.930
cynT
Carbonic anhydrase 1; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
 
0.923
can_2
Carbonic anhydrase family protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
 
0.914
focA
Putative formate transporter 1.
  
  
 0.834
thlA_2
acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family.
       0.798
ychM
Sulfate transporter family protein.
 
  
 0.757
yrdA
Bacterial transferase hexapeptide family protein.
    
 
 0.749
csgA
Short chain dehydrogenase family protein.
       0.711
aceK
Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.657
ychJ
Putative protein YchJ.
       0.642
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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