| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM82_3589 | aceK | DM82_3589 | DM82_3588 | Metallo-beta-lactamase superfamily protein. | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.498 |
| DM82_3605 | aceK | DM82_3605 | DM82_3588 | Hypothetical protein. | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.494 |
| aceA | aceB | DM82_1772 | DM82_1776 | Isocit_lyase: isocitrate lyase. | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | 0.999 |
| aceA | aceK | DM82_1772 | DM82_3588 | Isocit_lyase: isocitrate lyase. | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.920 |
| aceA | glcB | DM82_1772 | DM82_4412 | Isocit_lyase: isocitrate lyase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.991 |
| aceA | icd | DM82_1772 | DM82_286 | Isocit_lyase: isocitrate lyase. | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | 0.418 |
| aceB | aceA | DM82_1776 | DM82_1772 | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | Isocit_lyase: isocitrate lyase. | 0.999 |
| aceB | aceK | DM82_1776 | DM82_3588 | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | 0.527 |
| aceB | glcB | DM82_1776 | DM82_4412 | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.900 |
| aceB | icd | DM82_1776 | DM82_286 | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | 0.559 |
| aceB | thlA_2 | DM82_1776 | DM82_3586 | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.919 |
| aceK | DM82_3589 | DM82_3588 | DM82_3589 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Metallo-beta-lactamase superfamily protein. | 0.498 |
| aceK | DM82_3605 | DM82_3588 | DM82_3605 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Hypothetical protein. | 0.494 |
| aceK | aceA | DM82_3588 | DM82_1772 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Isocit_lyase: isocitrate lyase. | 0.920 |
| aceK | aceB | DM82_3588 | DM82_1776 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | malate_syn_A: malate synthase A; Belongs to the malate synthase family. | 0.527 |
| aceK | can_1 | DM82_3588 | DM82_3587 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Carbonic anhydrase family protein. | 0.657 |
| aceK | csgA | DM82_3588 | DM82_3585 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Short chain dehydrogenase family protein. | 0.590 |
| aceK | glcB | DM82_3588 | DM82_4412 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.457 |
| aceK | icd | DM82_3588 | DM82_286 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | Prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent. | 0.909 |
| aceK | thlA_2 | DM82_3588 | DM82_3586 | Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. | acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.639 |
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