Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM82_3589Metallo-beta-lactamase superfamily protein. (359 aa)    
Predicted Functional Partners:
wapA_2
Rhs_assc_core: RHS repeat-associated core domain protein.
   
    0.779
wapA_3
Rhs_assc_core: RHS repeat-associated core domain protein.
   
    0.779
DM82_996
Alpha/beta hydrolase fold family protein.
  
     0.596
aceK
Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
     
 0.531
lgrD_1
NRPS-para261: non-ribosomal peptide synthase TIGR01720 domain protein.
   
 
 0.520
tycC_2
AA-adenyl-dom: amino acid adenylation domain protein.
   
 
 0.520
folB
folB_dom: FolB domain protein.
 
     0.452
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
    0.447
DM82_3671
Hypothetical protein.
  
     0.446
DM82_4799
Rhodanese-like domain protein.
  
 
 0.434
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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